DRUG DISCOVERY & DEVELOPMENT

DRUG DISCOVERY & DEVELOPMENT Presents an Educational Webcast

11:00 a.m. ET; 8:00 a.m. PT • Wednesday, August 28, 2013 • Duration: 1 Hour

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Bioluminescence

Webcast Spotlight

resonance energy

Join us and learn about:

transfer has been long established as

• Promega's novel NanoBRET™

the principal

technology using NanoLuc™

method to monitor

and HaloTag ®

dynamic protein-

• Application of NanoBRET™

protein interactions

for measuring protein-protein

in living cells. However, the

interactions in living cells

application of BRET

• The new CLARIOstar ® high

is in general

performance multimode

hampered by its

microplate reader

limited dynamic range due to the

• The revolutionary new LVF

poor spectral

Monchromator™ from BMG

separation of donor

LABTECH

and acceptor. In

• Wavelength scanning in

this webcast we will

luminescence assays

introduce

• How to enhance all of your

NanoBRET™ using a donor/accpetor

assays with the CLARIOstar ®

combination

microplate reader.

consisting of NanoLuc™ luciferase and Halotag ® labeling technology.

The superior brightness of NanoLuc™ makes it ideally suited as an energy donor for BRET applications and allows the use of a novel red-shifted Halotag ® ligand as acceptor. The resulting increase in spectral separation between donor and acceptor translates into significantly improved dynamic range compared to current Rluc/YFP based BRET technology, which makes NanoBRET™ more suitable for the development of HTS compatible cell based protein-protein interaction assays.

For the NanoLuc ® BRET assay, two emission signals need to be measured at two different wavelength ranges. To get the best performance in this assay, wider bandwidths are preferred. Therefore, microplate readers that used filters with wider bandwidths always performed better in this assay than those instruments that used grating-based monochromators, which have fixed or adjustable bandwidths of < 25nm.

Until Now.

This webcast will highlight the performance of the NanoLuc ® BRET Assay from Promega on the new CLARIOstar ® multimode microplate reader from BMG LABTECH. Among many other great features, the CLARIOstar ® has a revolutionary new type of LVF Monochromator™ that has adjustable bandwidths from 8 to 100 nm.

PANELISTS MODERATOR

Tim Studt

E.J. Dell, Ph.D.

Thomas

Editorial Director

International

Machleidt, Ph.D.

Drug Discovery &

Marketing Director

Head of Cell

BMG LABTECH,

Biology,

Development

GmbH

Advanced Technology Group Promega Corporation

REMINDER: Attend this live webcast and pose your critical questions to the panel of experts during the live Q&A session during the broadcast.

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People & Power - Drug Money

Pharma Net Blogger

Investing in Pharmaceutical Companies

The pharmaceutical companies seem to be immune to the economic ups and downs that countries across the world go through. Illness and disease are an ongoing thing in life and it is due to this reason that the pharmaceutical companies have always been in business and were least affected by the economic ups and downs that have been experienced by different countries in the recent past. The global economies have been affected by recession, and most of the industries have been affected by the impact of recession. Banks have declared bankruptcy, automobile industry has got affected and even the service sector has laid-off so many people and this has all been a result of the recent recession.

However, the pharmaceutical industry has been able to sustain itself very well during all this time and continues to do so. Although e have seen mergers and acquisitions happening even in the pharmaceutical industry, yet the effect of recession on this industry has been much less when compared with the other industries.

For people thinking about investing in the pharmaceutical companies, there are a few pointers they might wish to know:

· Investing in this companies is not fool proof however if you compare it with any other industry, it would surely be rated as one of the most secure investments.

· Recession has not spared any segment or industry in the market today, each and every industry has felt the impact of the economic slowdown however all the different industries have felt the impact in varying degrees. The pharmaceutical industry has been affected the least but it too has not been able to totally escape the impact of recession.

· Illness and diseases are surely not affected by recession and that is one reason why the pharmaceutical companies have been able to comfortably sustain themselves during the economic slowdown. We have seen pharmaceutical companies merging and have also seen many people being laid off in this industry. Despite of these facts the pharmaceutical industry has shown less fluctuations in comparison to the banking and automobile industries.

· Investing in the pharmaceutical companies is still considered to be a very safe option in comparison to the automobile or banking sector. The reason for this is that the automobile industry has seen the shut down and merging of certain companies and the banking sector has seen the acquisition of many banks and also the filing of bankruptcy by some eminent banks in the past few years. While the pharmaceutical companies have also shown signs of being affected by the economic slowdown the magnitude of impact on pharmaceutical companies has been very low.

Keeping these few pointers in mind the general feeling in the investment market is that the pharmaceutical companies are a decent investment with safe return, especially in today's economically slow pace. Therefore most people are now skeptical about investing in other industries and choose to invest in the pharmaceutical companies so that they can experience the safety of their investment and not be bothered about a sudden shut down.

To find out more about investing in pharma companies you can go to http://www.medisan.com/. They also provide with many information and tips investing.

Article Source: EzineArticles.com