Search

Sunday, July 17, 2011

Fwd: | 07.11.11 | Jimenez: Novartis' desire for deals to return soon



-------- Original Message --------
Subject: | 07.11.11 | Jimenez: Novartis' desire for deals to return soon
Date: Mon, 11 Jul 2011 13:12:12 -0400 (EDT)
From: FiercePharma <editors@fiercepharma.com>
Reply-To: editors@fiercepharma.com
To: nbrauchitsch@yahoo.com


If you are unable to see the message below, click here to view.

July 11, 2011

Subscribe | Website | Jobs | Mobile
Refer FiercePharma to a Colleague

This week's sponsors:
INC Research
eKnowledgeBase
An Expert Briefing: Biotechnology 101
Thomson Reuters

Today's Top Stories:
1. Valeant snaps up Sanofi's Dermik for $425M
2. CEO: Novartis' desire for deals to return soon
3. Chinese docs trade up to jobs in pharma sales
4. Pfizer bids for $770M Lipitor extension in EU
5. Bayer's Yasmin to face EU generics this year

Spotlight:
Teva, Merck agree to 2017 date for Vytorin copies

Also Noted:
GSK wins FDA nod on Boostrix use; India's Orchid ordered to close API plant on pollution; Much more...

News From The Fierce Network:
1. Medtronic advises doctors of pump problem
2. QIAGEN amends offer for Cellestis
3. IBM cloud aids fight against superbugs


This week's sponsor is INC Research.

Sponsor:An Expert Briefing: Biotechnology 101

Webinars

> An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist

Events

> BioImmersion: Biotech for the Non-Scientist - July 13-15, 2011 - Chicago, IL
> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR
> Skill-building and Summer Fun in Boston!
> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL
> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA
> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

Jobs

> Regional BD Director
> Need a job? Need to hire? Visit FiercePharma and Biotech Jobs

This week's sponsor is eKnowledgeBase.

FREE two-week trial. Searchable online database providing access to verified company and drug competitive intelligence. Stay current on company, product, and pipeline performance/activity plus FDA actions, brand representation, and clinical initiatives. Click here.

Today's Top Stories

1. Valeant snaps up Sanofi's Dermik for $425M

By Tracy Staton Comment | Forward | < a href="http://links.mkt1985.com/ctt?kn=117&ms=MzUzODcxNwS2&r=MjM2NzI3MjAzMjcS1&b=0&j=MTExNTgxMDUwS0&mt=1&rt=0" name="api_addthis_com_oexchange_GB7wwdA5P9Sd7HQWWPr40A" >Twitter | Facebook | LinkedIn

Sanofi ($SNY) has agreed to offload its Dermik skincare business to Valeant Pharmaceuticals ($VRX) in a $425 million deal that gives the Canadian drugmaker brands such as the acne treatment BenzaClin and wrinkle-filler Sculptra. It also allows Sanofi to focus more tightly on what CEO Christopher Viehbacher (photo) calls its "growth platforms." 

The cash deal brings to fruition Sanofi's previously announced intent to divest the dermatology business with operations concentrated mostly in North America. "This divestiture allows us to rationalize our portfolio and improve focus on our core businesses," Viehbacher said in a statement.

Despite the "focus-on-our-core" language in that announcement, the Dermik sale isn't a divestment á la Bristol-Myers Squibb, which has pared away its non-pharma units to focus solely on innovative meds, or even a Pfizer-esque spinoff designed to feed investors' desires while shedding a big chunk of peripheral business. Sanofi, along with rivals such as GlaxoSmithKline and Novartis, remains in the diversification-is-good camp, with operations in animal health, consumer healthcare, generic drugs, et al, all intended to balance out the vagaries of today's prescription drug business.

For Valeant, the Dermik business is yet another to add to its quiver. Dermik has a manufacturing plant in Quebec, handy for the Canadian-based Valeant, and its dermatology drugs will help beef up the company's franchise in that area. While the other products are focused in North America, the aesthetic side of the business--a.k.a. Sculptra--has a global presence, giving Valeant a geographic footprint to build upon. "Dermik's assets, both in the medical and aesthetic therapeutic areas, provide us with exciting opportunities to leverage our combined portfolios in our current markets as well as options to expand Valeant's presence to other territories," CEO J. Michael Pearson said in a statement.

- see the release from Sanofi
- check out the Valeant announcement
- get more from Reuters

ALSO: Sanofi said Lemtrada, the experimental multiple sclerosis drug acquired through the purchase of Genzyme, helped patients more than Merck KGaA's older medicine Rebif in a key study. Report

Related Articles:
Valeant, J&J, Nestle nab new businesses
Valeant moves on to new M&A targets

Read more about: Valeant, Dermik, Sanofi-Aventis, Mergers and Acquisitions
back to top


An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist - Tuesday, July 26th, 1 pm ET / 10 am PT

Join us as we define biotechnology and briefly explore the various biotechnology sectors. We will also focus on the healthcare sector and explain how basic science and technology are used during the drug discovery process.
Topics include: DNA, Proteins, Recombinant DNA, Small and Large Molecule Drugs, and more Register today.


2. CEO: Novartis' desire for deals to return soon

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Novartis ($NVS) could soon be back on the acquisition trail. CEO Joe Jimenez (photo) told Swiss newspaper Aargauer Zeitung that the company's first priority is paying down $22 billion in debt, but strong cash flow should take care of that fairly quickly. And then, Novartis' appetite for deals is likely to sharpen, Reuters reports.

"We could soon be in the position to go for acquisitions again, even if they are not as big as Alcon," Jimenez told the Swiss newspaper. The Zurich-based drugmaker bought the eye-care company Alcon in a two-phase deal that wrapped up earlier this year.

Before that, Novatis snapped up other assets in smaller deals, such as the $400 million buyout of antibiotics company Protez Pharmaceuticals and the $932 million deal for Speedel Holding, its blood pressure drug partner.

Jimenez also said Novartis is on track to meet its goal of boosting sales by double-digits this year. Its margin-improvement goals are also doable, he said, measured in constant currencies. Half-year results are due July 19.

- read the news from Reuters
- get more from Bloomberg

Related Articles:
Will Novartis follow through with Gen-Probe bid?
Novartis scouts bolt-on deals of up to $3B
Novartis wraps up Alcon with $12.9B deal

Read more about: Novartis, Pharma buyout, Joe Jimenez
back to top


3. Chinese docs trade up to jobs in pharma sales

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

What's a low-paid Chinese doctor to do? Become a pharma rep. As Bloomberg reports, physicians in China are abandoning medical practice for jobs in drug sales, finding that they can better their $300-a-month doctors' salary by marketing drugs, rather than prescribing them. The human resources firm Aon predicts that as many as 14,000 Chinese doctors will join foreign drugmakers over the next 5 years.

Such is one unintended consequence of Big Pharma's Chinese gold rush. As drugmakers have laid off thousands of reps in the U.S. and Europe, they have been hiring big-time in emerging markets, especially China. The competition for drug reps in China is intense, too; turnover rates are high as major drugmakers such as Sanofi, Eli Lilly, Merck and Bayer recruit one another's salespeople.

Needless to say, doctors are highly in demand because of their specialized knowledge. "In most other countries, it's extremely rare to get fully trained doctors as medical representatives," Chris Lee, managing director of Bayer Healthcare China, told the news service.

Losing doctors to the drug business could exacerbate an existing shortage of physicians. China has only one doctor per every 7,000 people, and the government has been offering incentives such as free training to attract more people into primary care. Doctors willing to work in villages can win even more perks, such as relocation fees.

It's all part of China's effort to revamp its healthcare system, the very effort that has experts predicting big growth in the Chinese drug market for years to come. That growth, of course, has foreign drugmakers salivating--and jockeying for their share. As Bloomberg notes, Aon predicts that foreign pharma's Chinese offices will hire at least 35,000 sales staff by the end of 2014. That would more than double their sales force, which amounted to 33,000 at the end of 2010.

- read the Bloomberg story

Related Articles:
Nine of 10 Big Pharmas cut sales reps in 2010
Chinese pharma's a challenge on all sides

Read more about: China, Pharma sales reps
back to top


4. Pfizer bids for $770M Lipitor extension in EU

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Pfizer ($PFE) is poised for a Lipitor reprieve in Europe. The company has asked for 6 months' of additional exclusivity in most EU countries under regulations designed to promote pediatric drug trials. The extension could be worth almost $800 million as it staves off generic competition until May 2012, the Financial Times reports.

Pfizer is in line for the 6-month extension because of studies in children with a genetic disorder that causes high cholesterol. The company plans to launch a chewable, grape-flavored version of Lipitor in November as a result of those trials. "Pfizer certainly pulled off a bit of a coup," Heart UK's Dermot Neely told the FT.

The development is sparking some debate over the European pediatric trials regulations, which were instituted in 2007. But officials and experts say that the pediatric program has resulted in research that wouldn't have been conducted otherwise. "The regulations have been a big advance in developing medicines for children, but throw up some issues which it may be time to revisit," Alasdair Breckenridge, chairman of the UK's Medicines and Healthcare Products Regulatory Agency, told the newspaper.

Although the cholesterol fighter is already facing copycat rivals in some European countries--Spain, Finland and Norway--it's still under patent elsewhere in the EU. Pfizer has won or is seeking 6-month extensions in at least 11 other markets, the FT says, including the U.K., France and Germany.

- read the FT story

Related Articles:
Teva offers aid to U.K. pharmacies in Lipitor fight
Herper: Cheap Lipitor could increase health costs
Analysts: Lipitor may live longer than we think

Read more about: Europe, Pfizer, Lipitor
back to top


5. Bayer's Yasmin to face EU generics this year

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Bayer's birth-control franchise suffered a blow in Europe as patent regulators yanked protection on Yasmin. As the company's second-best-selling drug, Yasmin could now face generic competition later this year, Reuters notes.

The European Patent Office's ruling comes after an appeal from the Novartis generics unit Hexal, which had been fighting Bayer's patent on a procedure that reduces the size of particles containing Yasmin's active ingredient. That micronization patent would have been in force through 2020 thanks to officials' 2006 decision confirming the patent.

Now, Hexal is set to launch copies of Yasmin during the second half of this year, JP Morgan Cazenove analysts told investors after the ruling was announced. The European development comes after Yasmin lost patent protection in the U.S. last year. Sales in the states dropped last year to $1.6 billion.

The silver lining for Bayer, however, is that European pricing on Yasmin is much lower than in the U.S., giving cheaper generics a smaller cost advantage, analysts said. Plus, in most European markets, women pay out-of-pocket for contraceptives, meaning that insurers pushing for less-expensive copycat drugs might have less of an impact. "Although a negative surprise to the market, this event has a very modest impact to our valuation," UniCredit analyst Craig Maxwell told the news service.

- see the Reuters news

Related Articles:
FDA reviews risks of drospirenone contraceptives
Studies highlight clot risk with Bayer pills
Teva breaks deal with Bayer to launch Yaz copy

Read more about: Generics, Patent, Hexal, Yasmin
back to top


Also Noted

Spotlight On Obesity: A Pharma Matters Report

Download this insightful review from Thomson Reuters, which focuses on Obesity and looks at a relatively untapped market, in proportion to the scale of the potential market and the related diseases associated with obesity. Covered by this report is an in-depth critique of licensing, as companies strive to invest in the potentially profitable obesity drugs of the future. Click here to download the report.


TODAY'S SPOTLIGHT... Teva, Merck agree to 2017 date for Vytorin copies

Teva Pharmaceutical Industries has agreed that it won't sell generic versions of Merck's ($MRK) cholesterol drugs Vytorin and Zetia until 2017, settling patent disputes between the two companies. Merck still faces a patent fight with Mylan over Zetia and Vytorin, however. Report

@FiercePharma: Nine of 10 Big Pharmas cut sales reps in 2010. Report | Follow @FiercePharma

> The FDA has approved GlaxoSmithKline's Boostrix vaccine to prevent tetanus, diphtheria and whooping cough in people aged 65 and older. News

> Warner Chilcott said a U.S. federal court ordered a Boehringher Ingelheim unit not to launch a generic version of its inflammatory bowel treatment Asacol until Dec. 31. Story

> India's Orchid Chemicals & Pharmaceuticals said its API facility received a closure notice over disposal of solid waste, affecting its production of the antibiotic cephalosporin. Item

> Teva Pharmaceutical Industries faces two court hearings today. A U.S. court will consider the company's case against the developers of generic Copaxone, while a U.K. court will hear Pfizer's patent infringement case against Teva on Lipitor. Article

> Lonza, the world's biggest maker of drug ingredients, agreed to buy Arch Chemicals for $1.2 billion to create the global leader in the business of killing bacteria and fungi. Report

> Johnson & Johnson's Scios unit was charged by U.S. prosecutors with misbranding the heart drug Natrecor because the medicine's labeling allegedly lacked adequate directions for use. News

> Hikma Pharma said it purchased a significant minority interest in Hubei Haosun Pharmaceutical through the subscription of new equity for a cash consideration of $5 million. Item

> Dietary supplement manufacturer USANA Health Sciences Inc said it got approval from the FDA to make over-the-counter drugs. Article

> Belgian medical equipment and services company Arseus plans to buy a Brazilian peer for €51 million ($73 million) to secure the top spot in the world's largest pharmaceutical compound market. News

Biotech News

@FierceBiotech: Pfizer's potential offload of biz units could aid R&D prospects. Article | Follow @FierceBiotech

> Merrimack Pharma takes shot at $172.5M IPO with cancer contenders. Article 

> Sanofi MS drug shines, biotech strategy advances. Story

> Amgen widens cancer reach in $1B-plus Micromet deal. Item

Biotech IT News

> Two computational biology standouts honored. Report

> IBM cloud aids fight against superbugs. Story

> Health informatics giant Optum changes CEOs. Article

> Sequencing giant BGI advances in bioinformatics game. Report

> BioTox buys CRO Bio-Quant, eyes software integration. Story

> Biomolecular computer shows promise in detecting disease. Article

Medical Device News

> FDA may change premarket notification requirements for radiology devices. Report

> SurgiQuest closes $19M round. Piece

> QIAGEN amends offer for Cellestis, provides update on Ipsogen. News

> BD gets partial win in patent case. Story

> Medtronic advises doctors of pump problem. Article

> Medtronic buys two surgical products companies. Report

And Finally... An international research team has discovered a strain of gonorrhea resistant to all currently available antibiotics. Report

Webinars

> An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist

Join us Tuesday, July 26th, 1 pm ET / 10 am PT as we define biotechnology and briefly explore the various biotechnology sectors. We will also focus on the healthcare sector and explain how basic science and technology are used during the drug discovery process. Topics include: DNA, Proteins, Recombinant DNA, Small and Large Molecule Drugs, and more. Register Today

Events

> BioImmersion: Biotech for the Non-Scientist - July 13-15, 2011 - Chicago, IL

Three-day class delivering an in-depth understanding of both fundamental and advanced science and technology concepts. Focusing on the healthcare industry, participants learn about biologics- what they are, how they are discovered, how they are developed and how they are used as therapies. Learn More.

> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR

The world's leading clinical drug development and outsourcing event returns to Latin America for its 2nd Annual Partnerships in Clinical Trials Latin America meeting- bringing its unique formats, high-level strategic discussions, and unparalleled networking to Sao Paulo, Brazil. Visit www.PCTLA.com.

> Skill-building and Summer Fun in Boston!

Boston offers exciting summer options for visitors of all ages. You could see a movie in the local park, listen to a concert on City Hall Plaza, or learn to paint on the waterfront. So why not explore Boston in August and build your professional skills at the same time?

> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL

Medicaid Drug Rebate Program Summit is where manufacturers meet with all the government officials including CMS, VA, 340B, DoD, USDOJ and OIG for compliance and operations answers to healthcare reform questions. Register with a 25% off the standard rate by clicking here: www.medicaiddrugrebates.com

> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA

Led by Pfizer and Novartis, this groundbreaking conference delivers only case studies that demonstrate either a disruptive or an innovative approach to advancing clinical trials. Mobile Clinical Trials, Virtual Trials, Open Source Clinical Development are just a few examples of case studies featured. Fierce readers receive 15% off with code FBEL. Register or learn more: click here

> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Keynoted by Dr Robert Langer of MIT, this is a strategic level event for pharma and biotech BD&L executives to meet a wide range of drug delivery companies with the latest technologies. Fierce readers receive 15% off with code FBEL. Register or learn more: click here

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

With a surge in remote monitoring devices, mHealth developers are clamoring to build M2M applications that can transmit patient data in real time. Download this whitepaper today to learn more about developing apps for pharma-manufacturing and beyond. Download this white paper today!

Jobs

> Regional BD Director

We are considering candidates for a Regional Business Development (BD) Director to join our BD team! The ideal candidate should have specific experience calling on and selling into the R&D and clinical development/operations and study start up side of the industry, including but not limited to Phase I-IIIB as well as Phase IV post marketing surveillance, outcomes research and patient registry programs. Learn more.

> Need a job? Need to hire? Visit FiercePharma and Biotech Jobs

50+ new jobs just posted. Employers now post to the web site free. Find the perfect job or post your openings at FiercePharma Jobs.


©2011 FierceMarkets This email was sent to nbrauchitsch@yahoo.com as part of the FiercePharma email list which is administered by FierceMarkets, 1900 L Street NW, Suite 400, Washington, DC 20036, (202) 628-8778. Refer FiercePharma to a Colleague

Contact Us

Executive Editor: Ryan McBride. Managing Editor: Maureen Martino. Publisher: Arsalan Arif. VP, Sales: Ryan Willumson.

Advertise

Advertising/Lead-Generation: Ryan Willumson. Request a media kit.

Email Management

Manage your subscription

Change your email address

Unsubscribe from FiercePharma

Explore Our Network

You may enjoy these publications from FierceMarkets:

Fwd: | 07.14.11 | Merck job cuts to accelerate; Expect more pharma M&A, less hiring



-------- Original Message --------
Subject: | 07.14.11 | Merck job cuts to accelerate; Expect more pharma M&A, less hiring
Date: Thu, 14 Jul 2011 12:36:59 -0400 (EDT)
From: FiercePharma <editors@fiercepharma.com>
Reply-To: editors@fiercepharma.com
To: nbrauchitsch@yahoo.com


If you are unable to see the message below, click here to view.

July 14, 2011

Subscribe | Website | Jobs | Mobile
Refer FiercePharma to a Colleague

This week's sponsor:
INC Research
Sermo Surveys
eKnowledgeBase

Publisher's note:
Weekly Sermo Survey Partnership

Today's Top Stories:
1. Merck job cuts set to accelerate
2. Expect more pharma M&A, less pharma hiring
3. Yervoy may help BMS survive Euro-squeeze
4. French minister overhauls pharma regs
5. As Advair sales erode, Benlysta gets EMA nod

Spotlight:
FDA taps Dartmouth ex-dean for new post

Also Noted:
Elan to shutter 104-employee PA facility; Eisai to market Orion products in China; Much more...

News From The Fierce Network:
1. GSK gets Boostrix approval for adults over 65
2. Reps discuss Scottish device, diagnostic biz
3. GSK CEO: West can compete in manufacturing


This week's sponsor is INC Research.

Publisher's Note

Weekly Sermo Survey Partnership

Notice the physician survey we ran in yesterday's FiercePharma just below this space? Readers can now expect the same exclusive insight into physician sentiments every Wednesday thanks to an innovative new partnership we've struck with Sermo.

Sermo is a community of 120,000 doctors spanning 68 specialties collaborating on cases and discussing drugs and devices online. That network can power significant insights, providing our readers with more premium-level content you've come to enjoy from Fierce.  

Yesterday we learned what doctors think about the decline in the availability of pharmaceutical sales reps. Did they increase their use of digital tools to find information on drugs and devices? Do they replace a visit from a sales rep? What information would they prefer to see from those reps?

Readers are encouraged to check out this week's full analysis. I'm surprised to learn the percentage of doctors who claimed digital tools saved them time--it wasn't what I expected.

We'll be tweeting the surveys a few times a week using the #sermosurvey hashtag, and once FiercePharma's Facebook and LinkedIn communities launch later this summer, readers are welcome to share and discuss each week's findings there, too.

We strive to be the first place you turn for pharmaceutical industry news. Have any feedback on how Fierce continues serving your needs as a reader? Email me or find me on twitter. Thanks for being part of the Fierce community! - Arsalan Arif, Publisher

Webinars

> An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist

Events

> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR
> Skill-building and Summer Fun in Boston!
> Online Pharmaceutical & Healthcare Marketing MBA for Executives
> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL
> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA
> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

Jobs

> Regional BD Director
> Need a job? Need to hire? Visit FiercePharma and Biotech Jobs

Physicians' Perspective: Digital Tools and the Pharmaceutical Sales Representative
Sermo Study shows 78% of MDs Use Digital Tools to Gather Intelligence on Drugs/Devices
Are physicians turning to digital tools more to find information on drugs and devices? Find out what they had to say.

Sermo, the largest online physician network, announced a free report titled Physicians’ Perspective: Digital Tools and the Pharmaceutical Sales Representative. This report gathered feedback from physicians to understand their use of digital tools and how they effect sales representative meetings.

See the Complete Report


[Physicians: 97 respondents]
This week's sponsor is eKnowledgeBase.

FREE two-week trial. Searchable online database providing access to verified company and drug competitive intelligence. Stay current on company, product, and pipeline performance/activity plus FDA actions, brand representation, and clinical initiatives. Click here.

Today's Top Stories

1. Merck job cuts set to accelerate

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Merck's ($MRK) long-planned job cuts are set to accelerate. The company announced its intent to shed some 15,000 jobs by 2012 last year, but thousands of those jobs have yet to go. Sources tell Pharmalot that Merck plans to amp up its layoff process soon, probably early next month.

Merck announced the cuts in the wake of its 2009 merger with Schering-Plough. The idea was to save some $3.5 billion by slashing the payroll by 10% and shuttering facilities. Such an enormous restructuring plan takes time, of course, and as of March, Merck still had about 8,000 jobs remaining to be cut, Pharmalot figures.

Now, the layoffs will speed up, the blog's sources said. And they may not end with the announced 15,000. Company insiders tell Pharmalot that officials may want to cut the workforce even more than they had planned. Merck execs are combing operations for more ways to save money, they say. The company itself declined comment.

Merck's layoffs, while quite substantial, are still fewer than Pfizer's announced job cuts in association with its Wyeth merger. Other Big Pharma firms have cut back by the thousands as well.

- read the Pharmalot post

Related Articles:
Merck to close Inspire HQ, cut jobs
Pharma layoffs: 300K in 10 years
Merck puts off Dutch closures to renegotiate

Read more about: Merck, pharmaceutical layoffs
back to top


2. Expect more pharma M&A, less pharma hiring

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

If you're a pharma M&A junkie, then the next couple of years should make you happy. Unfortunately, the news isn't as good for those seeking a job in the drug industry. That's the message from a new KPMG survey of 100 pharma executives, many of whom expect difficult times ahead.

Some 83% of top pharma officials say they expect their companies to either buy or be bought over the next two years. Cash-rich drugmakers will continue their quest to restock pipelines and fill revenue gaps created by new generic competition. In addition, they're looking to further their geographic expansion by investing in deals or organic expansion into more emerging markets.

But all that emphasis on deals and expansion is defensive. Pharma executives still expect the business to be tough over the next several years, with the most optimistic 30% seeing economic recovery by the end of 2012 and the least-optimistic 27% predicting recovery by the end of 2014. "The good news is companies have cash to invest in or acquire new medicine breakthroughs, or markets and customers to drive some growth," KPMG partner David Blumberg said in a statement. In other words, in this economy, expect to buy growth, not fuel it from within.

No wonder, then, that the hiring picture looks pretty bleak. Only 41% of the executives said they'd be adding to their payrolls in 2012. Even more frightening: Almost one-quarter expect hiring to "never...return to pre-recession levels."

- read the KPMG release
- get more from the Philadelphia Inquirer
- see the coverage from PharmaExec

Related Articles:
N. American pharma buys drive up M&A prices
Burrill: A useless 10 years of pharma M&A
Dealmaking goes from mega to mini

Read more about: Mergers and Acquisitions, pharmaceutical hires
back to top


3. Yervoy may help BMS survive Euro-squeeze

By Tracy Staton Comment | Forward | < a href="http://links.mkt1985.com/ctt?kn=106&ms=MzU0NDQzMAS2&r=MjM2NzI3MjAzMjcS1&b=0&j=MTExNzIxMDQ1S0&mt=1&rt=0" name="api_addthis_com_oexchange_J5hc7JrL0IxUH1jHZ0gSA" >Twitter | Facebook | LinkedIn

Bristol-Myers Squibb ($BMY) is joining the chorus of drugmakers bewailing Europe's troubles. Economic crisis means cash-strapped countries aren't paying their bills on time, putting a pinch on pharma payables, BMS Europe chief Ron Cooper told Dow Jones. Meanwhile, drug-price cuts and austerity-level spending exacerbate the pain.

The sovereign debt crisis has an immediate effect on payables, Cooper said. It's not just Greece that's in arrears with pharma. "Many of these countries are taking increasing amounts of time to actually pay," he told Dow Jones. But it's also a longer-term threat, because financial limitations can in turn limit countries' willingness to pay for new meds.

However, luckily for BMS, it has a promising new drug to help offset these roadblocks to European growth. Yervoy, the company's breakthrough treatment for advanced melanoma, got the final nod from European regulators yesterday. Given that it's the first new treatment in decades, and the first approved treatment to significantly extend patients' lives, even budget-minded governments are likely to dig deep into their pocketbooks to pay the (steep) cost.

Pricing for Yervoy in Europe will be roughly equal to U.S. pricing: €21,000, or $29,927, compared with $30,000 per infusion. But Cooper figures that because of the small number of eligible patients, the impact on healthcare budgets will be limited, Reuters reports. BMS counts some 8,000 people have advanced melanoma in France, Italy, Germany, Britain and Spain combined.

"Our hope for continued growth in Europe is based on driving more volume and adding new products," Cooper told the news service. "Luckily we have a strong pipeline and that gives us opportunities to grow volume, sell new products and hopefully overcome some of those significant price impacts."

- get the release from BMS
- see the Dow Jones interview
- read the Reuters article

Related Articles:
Study: BMS drug works in untreated melanoma patients
ASCO spotlight on Yervoy, Zytiga and more
EMA nod for key new drugs from GSK, Merck, BMS

Read more about: Bristol-Myers Squibb, Europe, Yervoy
back to top


4. French minister overhauls pharma regs

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

The scandal surrounding Servier's Mediator drug in France has spawned a new approach to regulating pharma. Under pressure from an increasingly distrustful public, Health Minister Xavier Bertrand has proposed sweeping changes to France's regulatory framework, InPharm reports.

French regulators have been feeling the political heat from recent disclosures linking as many as 2,000 deaths with the now-withdrawn diabetes drug Mediator. The Servier drug was allowed to stay on the market in France after it had been withdrawn for safety reasons in other European markets. It was finally withdrawn there in November 2009. Some have blamed France-based Servier's close ties with doctors and regulators for Mediator's long stay on the market, InPharm notes.

The new regulations will require additional assessments of new drugs, mandate disclosures from industry and bar pharma funding of professional education. They'll also provide tighter controls on off-label prescribing. Mediator was often prescribed off-label in France for weight loss. Sales-rep visits to doctors would also be restricted. French lawmakers will begin considering the proposals this fall.

In the meantime, the ministry has begun reviewing 19,000 drugs currently approved in France. Bertrand predicts that many existing meds will be withdrawn because they can't demonstrate they're not inferior to other treatments.

- read the InPharm coverage

Related Articles:
Servier denies hiding risks of withdrawn diabetes drug
Servier founder to take stand in Mediator case
French patients, pols attack gov't over Mediator

Read more about: drug safety, Mediator, Servier
back to top


5. As Advair sales erode, Benlysta gets EMA nod

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Has GlaxoSmithKline's ($GSK) Benlysta hit the market just in time? As the company celebrated the FDA nod for its new lupus drug--to be marketed with partner Human Genome Sciences--and then wrapped up European approval, sales of its Advair respiratory drug began to decline. As PharmaTimes reports, the asthma and COPD treatment saw sales fall 7% in June, and year-to-date revenues have dropped by 5%.

Analysts are lamenting the decline, and some see it as a harbinger of worse to come. Generic versions are beginning to crop up, and Goldman Sachs expects copycat Advair to be widely available in Europe within 9 months. In fact, Goldman says pressure on the Advair franchise will cause the stock to underperform.

But on the bright side, GSK execs continue to maintain that Advair generics won't replicate the company's inhaler device, meaning that they won't be fully substitutable, and that, in turn, will help slow down generic adoption. And Matrix's Navid Malik backs up that view, PharmaTimes notes.

What's more, there's Benlysta. It has nabbed final EMA approval after U.S. approval in March. That's one reason why Malik is upbeat about GSK's near-term prospects. He figures the drug should counteract lack of confidence in the company's ability to pull off the kind of growth it needs in the next few years--and he expects GSK to manage top-line growth by next year, just as other Big Pharmas are suffering most.

- read the release from GSK
- see the Dow Jones news
- get more from PharmaTimes

Related Articles:
Sweden approves copy of GSK asthma blockbuster
GSK chief was right about tough-to-copy Advair
Now on the market, Benlysta meets skeptics
EMA nod for key new drugs from GSK, Merck, BMS

Read more about: Human Genome Sciences, Benlysta, GlaxoSmithKline, Advair
back to top


Also Noted

TODAY'S SPOTLIGHT... FDA taps Dartmouth ex-dean for new post

The FDA has named former Dartmouth Medical School dean Stephen Spielberg to the newly created position of deputy commissioner for medical products and tobacco as part of a management restructuring, according to an internal letter sent to agency employees. Report

@FiercePharma: Note to Pfizer: Bayer shopping for vet buys. Article | Follow @FiercePharma

> Elan is eliminating 104 jobs from a Pennsylvania facility that is part of the $960 million sale of its drug delivery unit to Alkermes deal. The facility is expected to be closed by September, the company tells Pharmalot. News

> Eisai has linked up with Orion to sell two of the Finnish drugmaker's breast cancer and Parkinson's disease treatments in China. Item

> Teva Pharmaceutical Industries completed its acquisition of Taiyo Pharmaceutical for $934 million in cash. Story

> Nigeria's second-largest drugmaker, May & Baker, plans to start exports to western and central Africa before the end of this year, CEO Nnamdi Okafor said. Article

> U.K. primary care trusts are not slashing the drugs budget as a cost-cutting move under the NHS' quality, innovation, productivity and prevention program, a leading official has told PharmaTimes. News

> Skin treatments supplier Sinclair IS Pharma said full year revenue raced ahead of expectations last year due to a strong performance in its fourth quarter and the contribution of its newly merged business. Report

Biotech News

@FierceBiotech: J&J's success with Hep C partners might hit a snag. Story | Follow @FierceBiotech

> Bristol-Myers grabs EU approval of key melanoma drug. Article 

> DVS Sciences lands $14.5M round with Big Pharma support. Report

> Verastem snags $32M for drugs against cancer stem cells. Item 

Manufacturing News

> Indian pharmas seek to protect their edge Report

> Corpedia, Second City bring comedy to compliance training. Item

> Hamburg appoints FDA deputies; Spielberg oversees drugs. Report 

> GSK's Witty: West can compete in manufacturing. Story 

> Pew track/trace call highlights congressional dallying. News  

> Expert: Boost audit programs to keep up with outsourcing More

Vaccines News

> With Gates Foundation backing, Liquidia advances novel flu vaccine. Item

> Shingles vaccination levels fall short of expectations. Report

> Crucell and Scripps find antibody for universal flu vax. News

> The CIA, bin Laden and the future of vaccine programs. Story

> GSK gets Boostrix approval for adults over 65. Article

> Microneedles may be better for H1N1 delivery. More

And Finally... People who regularly drink tea or coffee may be less likely to be carriers of the "superbug" MRSA, according to a U.S. study. Report

Webinars

> An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist

Join us Tuesday, July 26th, 1 pm ET / 10 am PT as we define biotechnology and briefly explore the various biotechnology sectors. We will also focus on the healthcare sector and explain how basic science and technology are used during the drug discovery process. Topics include: DNA, Proteins, Recombinant DNA, Small and Large Molecule Drugs, and more. Register Today

Events

> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR

The world's leading clinical drug development and outsourcing event returns to Latin America for its 2nd Annual Partnerships in Clinical Trials Latin America meeting- bringing its unique formats, high-level strategic discussions, and unparalleled networking to Sao Paulo, Brazil. Visit www.PCTLA.com.

> Skill-building and Summer Fun in Boston!

Boston offers exciting summer options for visitors of all ages. You could see a movie in the local park, listen to a concert on City Hall Plaza, or learn to paint on the waterfront. So why not explore Boston in August and build your professional skills at the same time?

> Online Pharmaceutical & Healthcare Marketing MBA for Executives

Saint Joseph's University offers an expanded portfolio of globally accessible AACSB-accredited programs ideal for working professionals in the pharma, biotech, medical device, diagnostics and healthcare sectors. Apply now; our September Cohort begins 9/8. Visit sju.edu/epharma or call 800-SJU-EMBA.

> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL

Medicaid Drug Rebate Program Summit is where manufacturers meet with all the government officials including CMS, VA, 340B, DoD, USDOJ and OIG for compliance and operations answers to healthcare reform questions. Register with a 25% off the standard rate by clicking here: www.medicaiddrugrebates.com

> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA

Led by Pfizer and Novartis, this groundbreaking conference delivers only case studies that demonstrate either a disruptive or an innovative approach to advancing clinical trials. Mobile Clinical Trials, Virtual Trials, Open Source Clinical Development are just a few examples of case studies featured. Fierce readers receive 15% off with code FBEL. Register or learn more: click here

> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Keynoted by Dr Robert Langer of MIT, this is a strategic level event for pharma and biotech BD&L executives to meet a wide range of drug delivery companies with the latest technologies. Fierce readers receive 15% off with code FBEL. Register or learn more: click here

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

With a surge in remote monitoring devices, mHealth developers are clamoring to build M2M applications that can transmit patient data in real time. Download this whitepaper today to learn more about developing apps for pharma-manufacturing and beyond. Download this white paper today!

Jobs

> Regional BD Director

We are considering candidates for a Regional Business Development (BD) Director to join our BD team! The ideal candidate should have specific experience calling on and selling into the R&D and clinical development/operations and study start up side of the industry, including but not limited to Phase I-IIIB as well as Phase IV post marketing surveillance, outcomes research and patient registry programs. Learn more.

> Need a job? Need to hire? Visit FiercePharma and Biotech Jobs

50+ new jobs just posted. Employers now post to the web site free. Find the perfect job or post your openings at FiercePharma Jobs.


©2011 FierceMarkets This email was sent to nbrauchitsch@yahoo.com as part of the FiercePharma email list which is administered by FierceMarkets, 1900 L Street NW, Suite 400, Washington, DC 20036, (202) 628-8778. Refer FiercePharma to a Colleague

Contact Us

Executive Editor: Ryan McBride. Managing Editor: Maureen Martino. Publisher: Arsalan Arif. VP, Sales: Ryan Willumson.

Advertise

Advertising/Lead-Generation: Ryan Willumson. Request a media kit.

Email Management

Manage your subscription

Change your email address

Unsubscribe from FiercePharma

Explore Our Network

You may enjoy these publications from FierceMarkets: