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Sunday, July 17, 2011

Fwd: | 07.14.11 | Merck job cuts to accelerate; Expect more pharma M&A, less hiring



-------- Original Message --------
Subject: | 07.14.11 | Merck job cuts to accelerate; Expect more pharma M&A, less hiring
Date: Thu, 14 Jul 2011 12:36:59 -0400 (EDT)
From: FiercePharma <editors@fiercepharma.com>
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To: nbrauchitsch@yahoo.com


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July 14, 2011

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This week's sponsor:
INC Research
Sermo Surveys
eKnowledgeBase

Publisher's note:
Weekly Sermo Survey Partnership

Today's Top Stories:
1. Merck job cuts set to accelerate
2. Expect more pharma M&A, less pharma hiring
3. Yervoy may help BMS survive Euro-squeeze
4. French minister overhauls pharma regs
5. As Advair sales erode, Benlysta gets EMA nod

Spotlight:
FDA taps Dartmouth ex-dean for new post

Also Noted:
Elan to shutter 104-employee PA facility; Eisai to market Orion products in China; Much more...

News From The Fierce Network:
1. GSK gets Boostrix approval for adults over 65
2. Reps discuss Scottish device, diagnostic biz
3. GSK CEO: West can compete in manufacturing


This week's sponsor is INC Research.

Publisher's Note

Weekly Sermo Survey Partnership

Notice the physician survey we ran in yesterday's FiercePharma just below this space? Readers can now expect the same exclusive insight into physician sentiments every Wednesday thanks to an innovative new partnership we've struck with Sermo.

Sermo is a community of 120,000 doctors spanning 68 specialties collaborating on cases and discussing drugs and devices online. That network can power significant insights, providing our readers with more premium-level content you've come to enjoy from Fierce.  

Yesterday we learned what doctors think about the decline in the availability of pharmaceutical sales reps. Did they increase their use of digital tools to find information on drugs and devices? Do they replace a visit from a sales rep? What information would they prefer to see from those reps?

Readers are encouraged to check out this week's full analysis. I'm surprised to learn the percentage of doctors who claimed digital tools saved them time--it wasn't what I expected.

We'll be tweeting the surveys a few times a week using the #sermosurvey hashtag, and once FiercePharma's Facebook and LinkedIn communities launch later this summer, readers are welcome to share and discuss each week's findings there, too.

We strive to be the first place you turn for pharmaceutical industry news. Have any feedback on how Fierce continues serving your needs as a reader? Email me or find me on twitter. Thanks for being part of the Fierce community! - Arsalan Arif, Publisher

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Events

> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR
> Skill-building and Summer Fun in Boston!
> Online Pharmaceutical & Healthcare Marketing MBA for Executives
> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL
> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA
> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

Jobs

> Regional BD Director
> Need a job? Need to hire? Visit FiercePharma and Biotech Jobs

Physicians' Perspective: Digital Tools and the Pharmaceutical Sales Representative
Sermo Study shows 78% of MDs Use Digital Tools to Gather Intelligence on Drugs/Devices
Are physicians turning to digital tools more to find information on drugs and devices? Find out what they had to say.

Sermo, the largest online physician network, announced a free report titled Physicians’ Perspective: Digital Tools and the Pharmaceutical Sales Representative. This report gathered feedback from physicians to understand their use of digital tools and how they effect sales representative meetings.

See the Complete Report


[Physicians: 97 respondents]
This week's sponsor is eKnowledgeBase.

FREE two-week trial. Searchable online database providing access to verified company and drug competitive intelligence. Stay current on company, product, and pipeline performance/activity plus FDA actions, brand representation, and clinical initiatives. Click here.

Today's Top Stories

1. Merck job cuts set to accelerate

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Merck's ($MRK) long-planned job cuts are set to accelerate. The company announced its intent to shed some 15,000 jobs by 2012 last year, but thousands of those jobs have yet to go. Sources tell Pharmalot that Merck plans to amp up its layoff process soon, probably early next month.

Merck announced the cuts in the wake of its 2009 merger with Schering-Plough. The idea was to save some $3.5 billion by slashing the payroll by 10% and shuttering facilities. Such an enormous restructuring plan takes time, of course, and as of March, Merck still had about 8,000 jobs remaining to be cut, Pharmalot figures.

Now, the layoffs will speed up, the blog's sources said. And they may not end with the announced 15,000. Company insiders tell Pharmalot that officials may want to cut the workforce even more than they had planned. Merck execs are combing operations for more ways to save money, they say. The company itself declined comment.

Merck's layoffs, while quite substantial, are still fewer than Pfizer's announced job cuts in association with its Wyeth merger. Other Big Pharma firms have cut back by the thousands as well.

- read the Pharmalot post

Related Articles:
Merck to close Inspire HQ, cut jobs
Pharma layoffs: 300K in 10 years
Merck puts off Dutch closures to renegotiate

Read more about: Merck, pharmaceutical layoffs
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2. Expect more pharma M&A, less pharma hiring

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

If you're a pharma M&A junkie, then the next couple of years should make you happy. Unfortunately, the news isn't as good for those seeking a job in the drug industry. That's the message from a new KPMG survey of 100 pharma executives, many of whom expect difficult times ahead.

Some 83% of top pharma officials say they expect their companies to either buy or be bought over the next two years. Cash-rich drugmakers will continue their quest to restock pipelines and fill revenue gaps created by new generic competition. In addition, they're looking to further their geographic expansion by investing in deals or organic expansion into more emerging markets.

But all that emphasis on deals and expansion is defensive. Pharma executives still expect the business to be tough over the next several years, with the most optimistic 30% seeing economic recovery by the end of 2012 and the least-optimistic 27% predicting recovery by the end of 2014. "The good news is companies have cash to invest in or acquire new medicine breakthroughs, or markets and customers to drive some growth," KPMG partner David Blumberg said in a statement. In other words, in this economy, expect to buy growth, not fuel it from within.

No wonder, then, that the hiring picture looks pretty bleak. Only 41% of the executives said they'd be adding to their payrolls in 2012. Even more frightening: Almost one-quarter expect hiring to "never...return to pre-recession levels."

- read the KPMG release
- get more from the Philadelphia Inquirer
- see the coverage from PharmaExec

Related Articles:
N. American pharma buys drive up M&A prices
Burrill: A useless 10 years of pharma M&A
Dealmaking goes from mega to mini

Read more about: Mergers and Acquisitions, pharmaceutical hires
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3. Yervoy may help BMS survive Euro-squeeze

By Tracy Staton Comment | Forward | < a href="http://links.mkt1985.com/ctt?kn=106&ms=MzU0NDQzMAS2&r=MjM2NzI3MjAzMjcS1&b=0&j=MTExNzIxMDQ1S0&mt=1&rt=0" name="api_addthis_com_oexchange_J5hc7JrL0IxUH1jHZ0gSA" >Twitter | Facebook | LinkedIn

Bristol-Myers Squibb ($BMY) is joining the chorus of drugmakers bewailing Europe's troubles. Economic crisis means cash-strapped countries aren't paying their bills on time, putting a pinch on pharma payables, BMS Europe chief Ron Cooper told Dow Jones. Meanwhile, drug-price cuts and austerity-level spending exacerbate the pain.

The sovereign debt crisis has an immediate effect on payables, Cooper said. It's not just Greece that's in arrears with pharma. "Many of these countries are taking increasing amounts of time to actually pay," he told Dow Jones. But it's also a longer-term threat, because financial limitations can in turn limit countries' willingness to pay for new meds.

However, luckily for BMS, it has a promising new drug to help offset these roadblocks to European growth. Yervoy, the company's breakthrough treatment for advanced melanoma, got the final nod from European regulators yesterday. Given that it's the first new treatment in decades, and the first approved treatment to significantly extend patients' lives, even budget-minded governments are likely to dig deep into their pocketbooks to pay the (steep) cost.

Pricing for Yervoy in Europe will be roughly equal to U.S. pricing: €21,000, or $29,927, compared with $30,000 per infusion. But Cooper figures that because of the small number of eligible patients, the impact on healthcare budgets will be limited, Reuters reports. BMS counts some 8,000 people have advanced melanoma in France, Italy, Germany, Britain and Spain combined.

"Our hope for continued growth in Europe is based on driving more volume and adding new products," Cooper told the news service. "Luckily we have a strong pipeline and that gives us opportunities to grow volume, sell new products and hopefully overcome some of those significant price impacts."

- get the release from BMS
- see the Dow Jones interview
- read the Reuters article

Related Articles:
Study: BMS drug works in untreated melanoma patients
ASCO spotlight on Yervoy, Zytiga and more
EMA nod for key new drugs from GSK, Merck, BMS

Read more about: Bristol-Myers Squibb, Europe, Yervoy
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4. French minister overhauls pharma regs

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

The scandal surrounding Servier's Mediator drug in France has spawned a new approach to regulating pharma. Under pressure from an increasingly distrustful public, Health Minister Xavier Bertrand has proposed sweeping changes to France's regulatory framework, InPharm reports.

French regulators have been feeling the political heat from recent disclosures linking as many as 2,000 deaths with the now-withdrawn diabetes drug Mediator. The Servier drug was allowed to stay on the market in France after it had been withdrawn for safety reasons in other European markets. It was finally withdrawn there in November 2009. Some have blamed France-based Servier's close ties with doctors and regulators for Mediator's long stay on the market, InPharm notes.

The new regulations will require additional assessments of new drugs, mandate disclosures from industry and bar pharma funding of professional education. They'll also provide tighter controls on off-label prescribing. Mediator was often prescribed off-label in France for weight loss. Sales-rep visits to doctors would also be restricted. French lawmakers will begin considering the proposals this fall.

In the meantime, the ministry has begun reviewing 19,000 drugs currently approved in France. Bertrand predicts that many existing meds will be withdrawn because they can't demonstrate they're not inferior to other treatments.

- read the InPharm coverage

Related Articles:
Servier denies hiding risks of withdrawn diabetes drug
Servier founder to take stand in Mediator case
French patients, pols attack gov't over Mediator

Read more about: drug safety, Mediator, Servier
back to top


5. As Advair sales erode, Benlysta gets EMA nod

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Has GlaxoSmithKline's ($GSK) Benlysta hit the market just in time? As the company celebrated the FDA nod for its new lupus drug--to be marketed with partner Human Genome Sciences--and then wrapped up European approval, sales of its Advair respiratory drug began to decline. As PharmaTimes reports, the asthma and COPD treatment saw sales fall 7% in June, and year-to-date revenues have dropped by 5%.

Analysts are lamenting the decline, and some see it as a harbinger of worse to come. Generic versions are beginning to crop up, and Goldman Sachs expects copycat Advair to be widely available in Europe within 9 months. In fact, Goldman says pressure on the Advair franchise will cause the stock to underperform.

But on the bright side, GSK execs continue to maintain that Advair generics won't replicate the company's inhaler device, meaning that they won't be fully substitutable, and that, in turn, will help slow down generic adoption. And Matrix's Navid Malik backs up that view, PharmaTimes notes.

What's more, there's Benlysta. It has nabbed final EMA approval after U.S. approval in March. That's one reason why Malik is upbeat about GSK's near-term prospects. He figures the drug should counteract lack of confidence in the company's ability to pull off the kind of growth it needs in the next few years--and he expects GSK to manage top-line growth by next year, just as other Big Pharmas are suffering most.

- read the release from GSK
- see the Dow Jones news
- get more from PharmaTimes

Related Articles:
Sweden approves copy of GSK asthma blockbuster
GSK chief was right about tough-to-copy Advair
Now on the market, Benlysta meets skeptics
EMA nod for key new drugs from GSK, Merck, BMS

Read more about: Human Genome Sciences, Benlysta, GlaxoSmithKline, Advair
back to top


Also Noted

TODAY'S SPOTLIGHT... FDA taps Dartmouth ex-dean for new post

The FDA has named former Dartmouth Medical School dean Stephen Spielberg to the newly created position of deputy commissioner for medical products and tobacco as part of a management restructuring, according to an internal letter sent to agency employees. Report

@FiercePharma: Note to Pfizer: Bayer shopping for vet buys. Article | Follow @FiercePharma

> Elan is eliminating 104 jobs from a Pennsylvania facility that is part of the $960 million sale of its drug delivery unit to Alkermes deal. The facility is expected to be closed by September, the company tells Pharmalot. News

> Eisai has linked up with Orion to sell two of the Finnish drugmaker's breast cancer and Parkinson's disease treatments in China. Item

> Teva Pharmaceutical Industries completed its acquisition of Taiyo Pharmaceutical for $934 million in cash. Story

> Nigeria's second-largest drugmaker, May & Baker, plans to start exports to western and central Africa before the end of this year, CEO Nnamdi Okafor said. Article

> U.K. primary care trusts are not slashing the drugs budget as a cost-cutting move under the NHS' quality, innovation, productivity and prevention program, a leading official has told PharmaTimes. News

> Skin treatments supplier Sinclair IS Pharma said full year revenue raced ahead of expectations last year due to a strong performance in its fourth quarter and the contribution of its newly merged business. Report

Biotech News

@FierceBiotech: J&J's success with Hep C partners might hit a snag. Story | Follow @FierceBiotech

> Bristol-Myers grabs EU approval of key melanoma drug. Article 

> DVS Sciences lands $14.5M round with Big Pharma support. Report

> Verastem snags $32M for drugs against cancer stem cells. Item 

Manufacturing News

> Indian pharmas seek to protect their edge Report

> Corpedia, Second City bring comedy to compliance training. Item

> Hamburg appoints FDA deputies; Spielberg oversees drugs. Report 

> GSK's Witty: West can compete in manufacturing. Story 

> Pew track/trace call highlights congressional dallying. News  

> Expert: Boost audit programs to keep up with outsourcing More

Vaccines News

> With Gates Foundation backing, Liquidia advances novel flu vaccine. Item

> Shingles vaccination levels fall short of expectations. Report

> Crucell and Scripps find antibody for universal flu vax. News

> The CIA, bin Laden and the future of vaccine programs. Story

> GSK gets Boostrix approval for adults over 65. Article

> Microneedles may be better for H1N1 delivery. More

And Finally... People who regularly drink tea or coffee may be less likely to be carriers of the "superbug" MRSA, according to a U.S. study. Report

Webinars

> An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist

Join us Tuesday, July 26th, 1 pm ET / 10 am PT as we define biotechnology and briefly explore the various biotechnology sectors. We will also focus on the healthcare sector and explain how basic science and technology are used during the drug discovery process. Topics include: DNA, Proteins, Recombinant DNA, Small and Large Molecule Drugs, and more. Register Today

Events

> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR

The world's leading clinical drug development and outsourcing event returns to Latin America for its 2nd Annual Partnerships in Clinical Trials Latin America meeting- bringing its unique formats, high-level strategic discussions, and unparalleled networking to Sao Paulo, Brazil. Visit www.PCTLA.com.

> Skill-building and Summer Fun in Boston!

Boston offers exciting summer options for visitors of all ages. You could see a movie in the local park, listen to a concert on City Hall Plaza, or learn to paint on the waterfront. So why not explore Boston in August and build your professional skills at the same time?

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Saint Joseph's University offers an expanded portfolio of globally accessible AACSB-accredited programs ideal for working professionals in the pharma, biotech, medical device, diagnostics and healthcare sectors. Apply now; our September Cohort begins 9/8. Visit sju.edu/epharma or call 800-SJU-EMBA.

> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL

Medicaid Drug Rebate Program Summit is where manufacturers meet with all the government officials including CMS, VA, 340B, DoD, USDOJ and OIG for compliance and operations answers to healthcare reform questions. Register with a 25% off the standard rate by clicking here: www.medicaiddrugrebates.com

> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA

Led by Pfizer and Novartis, this groundbreaking conference delivers only case studies that demonstrate either a disruptive or an innovative approach to advancing clinical trials. Mobile Clinical Trials, Virtual Trials, Open Source Clinical Development are just a few examples of case studies featured. Fierce readers receive 15% off with code FBEL. Register or learn more: click here

> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Keynoted by Dr Robert Langer of MIT, this is a strategic level event for pharma and biotech BD&L executives to meet a wide range of drug delivery companies with the latest technologies. Fierce readers receive 15% off with code FBEL. Register or learn more: click here

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

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Fwd: | 07.15.11 | U.K. workers dispute Novartis severance



-------- Original Message --------
Subject: | 07.15.11 | U.K. workers dispute Novartis severance
Date: Fri, 15 Jul 2011 12:07:13 -0400 (EDT)
From: FiercePharma <editors@fiercepharma.com>
Reply-To: editors@fiercepharma.com
To: nbrauchitsch@yahoo.com


If you are unable to see the message below, click here to view.

July 15, 2011

Subscribe | Website | Jobs | Mobile
Refer FiercePharma to a Colleague

This week's sponsors:
INC Research
eKnowledgeBase
An Expert Briefing: Biotechnology 101

Today's Top Stories:
1. U.K. workers dispute Novartis severance pay
2. Medicis shares drop on death at CEO's house
3. U.K. reforms leave NICE in judge's chair
4. Judge says Boehringer rep eligible for OT pay
5. Can generics biz cure a blockbuster hangover?

Spotlight:
Should pharma refocus on customers, not shareholders?

Also Noted:
J&J unit wraps up Russian OTC buy; Cephalon shareholders OK Teva deal; Much more...

News From The Fierce Network:
1. Transcend Medical boosts Series B to $51M
2. Vical, Astellas ink $130M vax licensing deal
3. Zyngenia grows with MedImmune vets at helm


This week's sponsor is INC Research.

Sponsor:An Expert Briefing: Biotechnology 101

Webinars

> An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist

Events

> Partnerships in Clinical Trials Latin America - Aug 2011 - Sao Paolo, BR
> Skill-building and Summer Fun in Boston!
> Online Pharmaceutical & Healthcare Marketing MBA for Executives
> 16th MDRP Summit - Sept. 14-16, 2011 - Marriott Downtown, Chicago, IL
> Disruptive Innovations in Clinical Trials - September 15-16, 2011 - Philadelphia, PA
> Partnership Opportunities in Drug Delivery - October 5-6, 2011 - Boston, MA

Marketplace

> Developing Enterprise M2M Apps in Days or Weeks - Not Months or Years

Jobs

> Regional BD Director
> Need a job? Need to hire? Visit FiercePharma and Biotech Jobs

This week's sponsor is eKnowledgeBase.

FREE two-week trial. Searchable online database providing access to verified company and drug competitive intelligence. Stay current on company, product, and pipeline performance/activity plus FDA actions, brand representation, and clinical initiatives. Click here.

Today's Top Stories

1. U.K. workers dispute Novartis severance pay

By Tracy Staton Comment | Forward | < a href="http://links.mkt1985.com/ctt?kn=81&ms=MzU0NjU4OQS2&r=MjM2NzI3MjAzMjcS1&b=0&j=MTExNzYyNjEyS0&mt=1&rt=0" name="api_addthis_com_oexchange_XdtDBUzqKNTm8pnrY0yQ" >Twitter | Facebook | LinkedIn

Layoffs are not a happy business in the best of circumstances. But when workers think they're being treated unfairly, tempers can really run high. Take the job cuts at Novartis' ($NVS) facility in Horsham, England. The company announced in March that it would slice 550 positions from the plant's workforce. And as the cuts move ahead, employees are protesting.

As the West Sussex County Times reports, 150 workers at the Horsham facility are balking at their severance settlements. The workers have been offered two weeks' pay for each year served--which might have been fine, had they not heard that downsized employees at Novartis' Liverpool facility were offered twice that much. The difference, the workers claim, is that Liverpool's staff is unionized, while Horsham's is not.

In Liverpool, 190 workers face losing their jobs, but the UNITE union negotiated a four-weeks-per-year-of-service severance deal with the company. The Horsham workers filed a grievance to protest the difference, saying that the company had discriminated against non-union employees. After a three-month review process, the company determined that there was no discrimination, the Times reports.

The reported discrepancies have angered and disillusioned workers and the local community. In the past, Novartis has been praised as a good corporate citizen and an "exceptionally good employer." The company will continue to operate at Horsham, with a workforce of at least 330, The Argus reports.

For its part, the company issued a statement to the paper. "[A]ll redundant employees will be offered a severance package that will be enhanced from that required by statute." The company said it had considered "all counterproposals" made by employees, and that other assistance will be provided, including outplacement services and opportunities for alternate jobs elsewhere. The severance packages now await final approval, the company said.

- read the County Times story
- get more from The Argus

Related Articles:
Merck job cuts set to accelerate
Novartis dismisses senior staffers for misconduct
Novartis to slice 500 jobs from UK facility

Read more about: Novartis, pharmaceutical layoffs
back to top


An Expert Briefing: Biotechnology 101- An Industry Overview for the Non-Scientist - Tuesday, July 26th, 1 pm ET / 10 am PT

Join us as we define biotechnology and briefly explore the various biotechnology sectors. We will also focus on the healthcare sector and explain how basic science and technology are used during the drug discovery process.
Topics include: DNA, Proteins, Recombinant DNA, Small and Large Molecule Drugs, and more Register today.


2. Medicis shares drop on death at CEO's house

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

When do a CEO's personal problems become worrisome to investors? Well, it depends on the problem. In the case of Medicis Pharmaceutical chief Jonah Shacknai, the answer is, "Almost immediately." Two days after his 6-year-old son suffered critical injuries from a fall down a staircase at his Coronado, CA, house, Shacknai's live-in girlfriend was found bound, nude, and hanging from a balcony there. Within hours of the news, the company's stock plummeted.

Word is that Shacknai and his ex-wife were at the hospital with their injured son when the woman was found. Shacknai's brother Adam, who was staying in a guesthouse on the property, cut the woman down and called police, the Los Angeles Times reports. After initial evidence-gathering, the San Diego County Sheriff's Department and Coronado Police were saying they didn't know whether the death was murder or suicide. They have found no link between the boy's fall and the woman's death.

"We have not determined if this is criminal or if this is a death investigation," Capt. Tim Curran of the sheriff's department told the Wall Street Journal. "Whether it is a homicide or a suicide, it is one of the most bizarre and unusual cases we have ever seen."

Piper Jaffray analyst David Amsellem called the stock drop "just a little panic selling," Bloomberg reports. "There's no question that Jonah is very much the face of the company and very much a part of the overall vision and strategy," Ansellem said, but added that the company's day-to-day operations aren't likely to be affected by the Shacknai tragedies. Medicis has "very good bench strength," he said.

- see the WSJ coverage
- get more from Bloomberg
- read the LA Times article
- check out the Reuters news

Related Articles:
Allergan, Medicis lobby hard against 'Botax'
Medicis, Allergan fight for wrinkle-fighting consumers

Read more about: Medicis Pharmaceutical, Jonah Shacknai
back to top


3. U.K. reforms leave NICE in judge's chair

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Remember the reports that the U.K.'s cost-effectiveness watchdog would be shunted aside as the country adopts value-based pricing? Well, scratch that. As the government rethinks proposed National Health Service reforms, it's also reconsidering its overhaul of the drug-pricing chain of command.

Yes, the U.K. health system will be moving to value-based pricing--whatever that turns out to mean--by 2014. But the National Institute for Health and Clinical Excellence won't become an advisory body whose decisions about cost-effectiveness are only, well, advisory. NICE will keep its teeth, agency chief Andrew Dillon told Reuters. It will still have the authority to decide which treatments should be used by NHS.

So, how might NICE work in the value-based pricing era? The new scheme will aim to put higher prices on drugs that are most effective, most innovative and address unmet medical needs. NICE is likely to set up a series of cost-effectiveness brackets to help companies determine where new products are likely to fall, Reuters reports. "The government wants a system that is as predictable as possible...so that it will be very easy for companies to work out whether or not the NHS is likely to find their price acceptable," Dillon said (as quoted by the news service).

And if NICE doesn't accept a company's proposed price? All this has yet to be worked out, but Dillon took a stab at it. "[I]f the price is beyond the relevant threshold," he said, "then my assumption is that would trigger negotiations between the government and the pharmaceutical company."

- get the Reuters news
- see the InPharm coverage

ALSO: Novartis failed to win approval from the U.K.'s health-cost agency for its drug Lucentis in diabetics who suffer an eye condition. Report

Related Articles:
U.K. doc says GPs don't want NICE's job
U.K. earmarks £200M for NICE-rejected drugs
NICE to be sidelined, minister confirms

Read more about: drug prices, NICE, United Kingdom
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4. Judge says Boehringer rep eligible for OT pay

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Time to update your sales-rep overtime scorecard. A federal judge has ruled that a Boehringer Ingelheim rep is not exempt from overtime pay under the Fair Labor Standards Act, Pharmalot reports. It's just the latest decision in the ongoing legal battle between salespeople, who say they deserve OT, and drugmakers, who consider their reps "outside salespeople" who don't qualify.

In the Boehringer case, Judge Ursula Ungaro determined that plaintiff Graciela Palacios not only was not an outside salesperson, but that she did not fit the FSLA's administrative exemption, either. That exemption applies to management and professional types who are able to act on their own discretion and use independent judgment at work, as Pharmalot notes. Ungaro said the Boehringer rep's job did not fit that description.

The summary judgment comes after the U.S. Supreme Court passed on an opportunity to review appeals court decisions granting overtime to reps for Novartis and Schering-Plough. That choice essentially ratified the Second Circuit's ruling, which means that similar lawsuits in that Circuit--such as those pending against Pfizer, Abbott Laboratories and Bristol-Myers Squibb--are likely to go the same way.

But another circuit court--the Ninth--has ruled for GlaxoSmithKline in an OT dispute with reps. Amgen and Johnson & Johnson's Ortho-McNeil unit are on the no-overtime side of the ledger, too. How all the different suits in different jurisdictions will shake out remains to be seen. But some legal experts expect the Supreme Court to end up intervening at some point.

- see the Pharmalot post

Related Articles:
Laid-off Pfizer reps join OT lawsuit
Sales reps win as Supremes refuse overtime appeals
Labor agency jumps into another sales-rep overtime case
The tough life of a pharma sales rep

Read more about: lawsuit, Supreme Court, Boehringer Ingelheim, Pharma sales reps
back to top


5. Can generics biz cure a blockbuster hangover?

By Tracy Staton Comment | Forward | Twitter | Facebook | LinkedIn

Anyone who's been watching pharma knows that the number of big new drugs has been dropping. That's obviously a problem for Big Pharma. But it's going to become a problem for branded drugmakers' major nemesis: the generics industry. Makers of copycat meds like to knock off blockbusters because they stand to deliver more return on the up-front investment. As branded drugmakers increasingly turn out smaller, more specialized meds, there will be fewer big drugs to copy.

Much has been made of the fact that Big Pharma's patent losses over the next few years will be the generics business's gain. Drugs accounting for billions in sales are falling off patent, and copycat drugmakers will reap the benefits from that steady stream of big new products. It's like a baby boom; after the boom generation moves through, there's a bust. The difficulty branded drugmakers have had in getting new meds approved means that there will be fewer products for generics makers to copy as time goes on.

"What has happened is that the approval of new products over the last many years has not gone significantly beyond 25-30 per year. And not many of these products have become very large," Sun Pharmaceutical Chairman Dilip Shanghvi told MarketWatch. "All of this has created a challenge both for Big Pharma as well as the generic industry."

And what do leading generics companies plan to do to deal with that eventuality? The strategies will sound familiar. They're eyeing geographical expansion in emerging markets and preparing for possible consolidation through M&A. And they're also looking to build up businesses in brand-name specialty drugs. All strategies that Big Pharma is using right now to deal with its own blockbuster withdrawal.

In his interview with MarketWatch, Shanghvi talked about possible acquisitions in emerging markets, as well as organic growth in those countries, partly through a partnership with Merck. Brand-name specialty meds are in his sights, too. "[I]t's natural for us to also look at growing by becoming a specialty pharma company," he said. "Because then we can introduce our own products and use those for future growth."

- read the MarketWatch interview

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Read more about: Brand Name Drugs, Generics, Generic drugs, emerging pharmaceutical markets
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Saturday, May 28, 2011

INVESTMENTS IN PHARMACEUTICALS

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THE R&D INDICATOR
The amount of money a corporation spends on research and development is a: good guide to its earnings prospects.  Generally, the higher the expenditure in relation to sales, the greater the company’s emphasis on new-product development Benchmark: 5 % of annual sales spent on research is considered a sizable commitment to research spending.  Source:  Merrill Lynch Stockfinder Research Service, 165 Broadway, New York 10080.  

OPTIONS AS INDICATORS
Often the first sign of a rally in a stock is increased activity in its options Recommended: Look for newcomers on the “Most Active Options” list in The Wall Street Journal  Then, all you have to remember is …sell high…buy low...Happy climbing!

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